A batch of labelled eppendorf tubes
Eppendorf tubes in an Oxford laboratory
(Image Credit: Rob Judges / Oxford University Images)

DPhil in Biochemistry (Skaggs-Oxford Programme)

About the course

The Skaggs-Oxford Programme is a joint five-year programme in biology or chemistry at Scripps Research based in either La Jolla, California or Jupiter, Florida, and the Department of Biochemistry at the University of Oxford, leading to the award of a joint PhD/DPhil degree.

The joint Skaggs-Oxford Programme permits highly qualified students to gain a broader and deeper interdisciplinary research experience than is possible from a single institution's doctoral programme. It provides diversity in curriculum, scientific approaches and research training, with access to facilities and expertise at both  the University of Oxford and Scripps Research. It also offers the experience of the distinct cultures of the United States and the United Kingdom.

You will have the option of beginning the full programme of study either at Oxford or at Scripps Research. 

You can choose from a wide range of research areas covered by the University of Oxford's Department of Biochemistry and Scripps Research's Departments of Chemistry, Immunology and Microbiology, Integrative Structural and Computational Biology, Molecular Medicine, and Neuroscience.

Research areas include: ageing, cancer biology, cell biology, chemical biology, chromosome biology, chemical synthesis, drug discovery and vaccine design, epigenetics, host-pathogen interactions, infectious diseases (such as HIV, Ebola and Zika), innate and responsive immune systems, medicinal chemistry, membrane proteins, neural stem cell behaviour and development of the brain and sensory organs, ion channels and transporters, and RNA biology.

Whilst working on your research project you will participate in a comprehensive, flexible skills training programme which includes a range of workshops and seminars in transferable skills, generic research skills and specific research techniques. There are also numerous seminars and lectures by local and visiting scientists, which bring students together with academic and other research staff in the department to hear about on-going research, and provide an opportunity for networking and socialising.

Attendance

The course is full-time and requires attendance in Oxford. Full-time students are subject to the University's Residence requirements.

You will be required to carry out research for a minimum of two years at Oxford.

Provision exists for students on some courses to undertake their research in a ‘well-founded laboratory’ outside of the University. This may require travel to and attendance at a site that is not located in Oxford. Where known, existing collaborations will be outlined on this page. Please read the course information carefully, including the additional information about course fees and costs. 

Resources to support your study

As a graduate student, you will have access to the University's wide range of world-class resources including libraries, museums, galleries, digital resources and IT services.

The Bodleian Libraries is the largest library system in the UK. It includes the main Bodleian Library and libraries across Oxford, including major research libraries and faculty, department and institute libraries. Together, the Libraries hold more than 13 million printed items, provide access to e-journals, and contain outstanding special collections including rare books and manuscripts, classical papyri, maps, music, art and printed ephemera.

The University's IT Services is available to all students to support with core university IT systems and tools, as well as many other services and facilities. IT Services also offers a range of IT learning courses for students, to support with learning and research.

You will also have access to: 

The provision of project-specific resources will be agreed with the relevant supervisor during the planning stages of the research project.

There is the possibility to use facilities outside of the Biochemistry department in other departments across the division and to access remote facilities at the Rutherford Appleton Laboratory, DIAMOND Light Source and Harwell Science and Innovation Campus.

Supervision

For this course, the allocation of graduate supervision is the responsibility of the University of Oxford's Department of Biochemistry and Scripps Research. Please note that it is not always possible to accommodate the preferences of incoming graduate students to work with a particular member of staff.

Your supervisor may appoint a senior member of the laboratory as your day-to-day supervisor.

Most students have an opportunity to meet their supervisor on a weekly or fortnightly basis. In addition, Most laboratories also have weekly meetings where members present and discuss their results with other members of the laboratory.

Information about Oxford supervisors connected with this course can also be found at the Department of Biochemistry website. 

Assessment

Starting at the University of Oxford

If you begin your programme of study at Oxford, you will start your course as a probationary research student (PRS) and apply to transfer to DPhil (PhD) status near the end of your first year. Your application to transfer will involve you writing a research report and statement of future research plans. This will be assessed by two independent experts, who interview you as part of the process. Continuation in the programme is subject to passing the Transfer of Status exam.

Starting at Scripps Research

If you begin your programme of study at Scripps Research, you will also start your course as a probationary research student (PRS). You will be required to undertake a sequence of taught coursework in connection with your proposed field of research, unless you are granted an exemption in recognition of study and examinations previously undertaken. Courses are graded based on written assignments and a final written exam. You will typically apply to transfer to DPhil (PhD) status near the end of your second year. Your application to transfer will involve you writing a research report and statement of future research plans. This will be assessed by two independent experts, who interview you as part of the process. Continuation in the programme is subject to passing the Transfer of Status exam.

Common assessment elements

After three years of study you will need to apply formally to confirm your DPhil (PhD) status. This involves writing a short progress report and thesis outline and giving a presentation. The application is assessed by two experts. Continuation in the programme is subject to successfully completing the Confirmation of Status.

The final stage of the research programme is submission of your DPhil thesis, which needs to be done within five years. Your thesis is assessed by two independent experts (one from Oxford and one who is external to the University of Oxford and Scripps Research) and your Thesis Committee at Scripps Research, who conduct a viva examination with you.

Successful candidates are awarded a degree certificate from Scripps Research and the University of Oxford. They are invited to attend ceremonies at both institutions.

Graduate destinations

The majority of alumni go on to pursue a career within academic or industrial research.

Changes to this course and your supervision

The University will seek to deliver this course in accordance with the description set out in this course page. However, there may be situations in which it is desirable or necessary for the University to make changes in course provision, either before or after registration. The safety of students, staff and visitors is paramount and major changes to delivery or services may have to be made if a pandemic, epidemic or local health emergency occurs. In addition, in certain circumstances, for example due to visa difficulties or because the health needs of students cannot be met, it may be necessary to make adjustments to course requirements for international study.

Where possible your academic supervisor will not change for the duration of your course. However, it may be necessary to assign a new academic supervisor during the course of study or before registration for reasons which might include illness, sabbatical leave, parental leave or change in employment.

For further information please see our page on changes to courses and the provisions of the student contract regarding changes to courses.

Initial assessment by Scripps Research

Your application will initially be assessed by Scripps Research against the 'Admission Guidelines' published on the Scripps Research website

If your application passes this initial assessment, you will be invited to submit an application to the University of Oxford (please refer to the How to Apply section of this page for further details). A successful application to the University of Oxford is a requirement of entry to this course. Your application to the University of Oxford will be assessed against the entry requirements shown below, alongside applicants to the DPhil in Biochemistry. An interview with the University of Oxford will be conducted following your application to the University of Oxford and if successful a second interview will take place with Scripps Research. 

Entry requirements for entry in 2025-26

Proven and potential academic excellence

The requirements described below are specific to this course and apply only in the year of entry that is shown. You can use our interactive tool to help you evaluate whether your application is likely to be competitive.

We know that factors such as socio-economic circumstances and school performance can make it difficult for students to demonstrate their full potential. This course is taking part in an initiative to use contextual data to help us to better understand your achievements in the context of your individual background. For further details, please refer to the information about improving access to graduate study in the How to apply section of this page.

Please be aware that any studentships that are linked to this course may have different or additional requirements and you should read any studentship information carefully before applying. Contextual data may also be used in the assessment of studentships. 

Degree-level qualifications

As a minimum, applicants should hold or be predicted to achieve the following UK qualifications or their equivalent:

  • a first-class or strong upper second-class undergraduate degree with honours.

The qualification above should be achieved in one of the following subject areas or disciplines:

  • biochemistry
  • chemistry
  • biology
  • cell biology
  • molecular biology
  • biophysics
  • physics
  • mathematics
  • computation.

Please note that entrance is very competitive and most successful applicants have a first-class degree. 

A previous master's degree is not required in order to be considered for the programme.

For applicants with a degree from the USA, the minimum overall GPA that is normally required to meet the undergraduate-level requirement is 3.5 out of 4.0. However, most successful applicants have a GPA of 3.7. 

If your degree is not from the UK or another country specified above, visit our International Qualifications page for guidance on the qualifications and grades that would usually be considered to meet the University’s minimum entry requirements.

GRE General Test scores

No Graduate Record Examination (GRE) or GMAT scores are sought.

Other qualifications, evidence of excellence and relevant experience

  • Applicants are normally expected to have research experience in a biomedical or scientific field. Examples of suitable research experience include, but are not limited to, research projects carried out during previous degree-level study, research internships or work experience as a research assistant
  • A track record demonstrating an interest in research, including the ability to master technical/computational skills, and plan and execute experiments effectively, is likely to advantage your application
  • You are expected to have a good understanding of your proposed area of research and be familiar with the recent published work of your proposed supervisor(s)
  • Applicants are not required to have publications, but it may strengthen your application if you have already published your work in a scientific journal.

English language proficiency

This course requires proficiency in English at the University's standard level. If your first language is not English, you may need to provide evidence that you meet this requirement. The minimum scores required to meet the University's standard level are detailed in the table below.

Minimum scores required to meet the University's standard level requirement
TestMinimum overall scoreMinimum score per component
IELTS Academic (Institution code: 0713) 7.06.5

TOEFL iBT, including the 'Home Edition'

(Institution code: 0490)

100Listening: 22
Reading: 24
Speaking: 25
Writing: 24
C1 Advanced*185176
C2 Proficiency185176

*Previously known as the Cambridge Certificate of Advanced English or Cambridge English: Advanced (CAE)
Previously known as the Cambridge Certificate of Proficiency in English or Cambridge English: Proficiency (CPE)

Your test must have been taken no more than two years before the start date of your course. Our Application Guide provides further information about the English language test requirement.

Declaring extenuating circumstances

If your ability to meet the entry requirements has been affected by the COVID-19 pandemic (eg you were awarded an unclassified/ungraded degree) or any other exceptional personal circumstance (eg other illness or bereavement), please refer to the guidance on extenuating circumstances in the Application Guide for information about how to declare this so that your application can be considered appropriately.

References

You will need to register three referees who can give an informed view of your academic ability and suitability for the course. The How to apply section of this page provides details of the types of reference that are required in support of your application for this course and how these will be assessed.

Supporting documents

You will be required to supply supporting documents with your application. The How to apply section of this page provides details of the supporting documents that are required as part of your application for this course and how these will be assessed.

Performance at interview

Interviews are normally held as part of the admissions process.  

Applications are reviewed by a panel of academics associated with the course. A short-list of applicants is confirmed, based on assessment of achieved or predicted undergraduate degree grade, academic references, personal statement and CV.

Interviews are in person or by video link and are conducted by a panel of at least two interviewers. Applicants are asked to talk about any research project(s) that they may have pursued and questioned on aspects of their research training to date, understanding of the proposed area of study and motivation for undertaking a DPhil.

Following a successful interview with the University of Oxford, shortlisted candidates will be interviewed separately by Scripps Research in the final stage of the application process.

Offer conditions for successful applications

If you receive an offer of a place at Oxford, your offer will outline any conditions that you need to satisfy and any actions you need to take, together with any associated deadlines. These may include academic conditions, such as achieving a specific final grade in your current degree course. These conditions will usually depend on your individual academic circumstances and may vary between applicants. Our 'After you apply' pages provide more information about offers and conditions

In addition to any academic conditions which are set, you will also be required to meet the following requirements:

Financial Declaration

If you are offered a place, you will be required to complete a Financial Declaration in order to meet your financial condition of admission.

Disclosure of criminal convictions

In accordance with the University’s obligations towards students and staff, we will ask you to declare any relevant, unspent criminal convictions before you can take up a place at Oxford.

Academic Technology Approval Scheme (ATAS)

Some postgraduate research students in science, engineering and technology subjects will need an Academic Technology Approval Scheme (ATAS) certificate prior to applying for a Student visa (under the Student Route). For some courses, the requirement to apply for an ATAS certificate may depend on your research area.

Other factors governing whether places can be offered

The following factors will also govern whether candidates can be offered places:

  • the ability of the University to provide the appropriate supervision for your studies, as outlined under the 'Supervision' heading in the About section of this page;
  • the ability of the University to provide appropriate support for your studies (eg through the provision of facilities, resources, teaching and/or research opportunities); and
  • minimum and maximum limits to the numbers of students who may be admitted to the University's taught and research programmes.

Biochemistry

The Department of Biochemistry comprises over 45 research groups and around 400 researchers and support staff, including more than 100 graduate students.

The Department of Biochemistry is a vibrant research and teaching department and benefits from state-of-the-art research facilities in its stunning purpose-built building. These include advanced fluorescence microscopy, advanced proteomics, NMR spectroscopy, molecular biophysics, and crystallography.

Research in the department is very broad and encompasses all aspects of modern molecular and cellular biochemistry, from atomic resolution biophysics to cell biology and imaging. The quality of research is outstanding, as demonstrated by an impressive publications output and the international standing of many of the department's researchers.

Funding and costs

Information about course fees

Course fees are payable each year, for the duration of your fee liability (your fee liability is the length of time for which you are required to pay course fees). For courses lasting longer than one year, please be aware that fees will usually increase annually. For details, please see our guidance on changes to fees and charges.

Course fees cover your teaching as well as other academic services and facilities provided to support your studies. Unless specified in the additional information section below, course fees do not cover your accommodation, residential costs or other living costs. They also don’t cover any additional costs and charges that are outlined in the additional information below.

Continuation charges

Following the period of fee liability, you may also be required to pay a University continuation charge and a college continuation charge. The University and college continuation charges are shown on the Continuation charges page.

Where can I find further information about fees?

The Fees and Funding section of this website provides further information about course fees payable to the University of Oxford, including information about fee status and eligibility and your length of fee liability. The Scripps Research website provides information about fees payable at Scripps Research California Campus.

Additional information

Living costs

In addition to your course fees and any additional course-specific costs, you will need to ensure that you have adequate funds to support your living costs for the duration of your course.

Living costs for full-time study

For the 2025-26 academic year, the range of likely living costs for a single, full-time student is between £1,425 and £2,035 for each month spent in Oxford. We provide the cost per month so you can multiply up by the number of months you expect to live in Oxford. Depending on your circumstances, you may also need to budget for the costs of a student visa and immigration health surcharge and/or living costs for family members or other dependants that you plan to bring with you to Oxford (assuming that dependant visa eligibility criteria are met).

Further information about living costs

The current economic climate and high national rate of inflation make it very hard to estimate potential changes to the cost of living over the next few years. For study in Oxford beyond the 2025-26 academic year, it is suggested that you budget for potential increases in living expenses of around 4% each year – although this rate may vary depending on the national economic situation. For further information, please consult our more detailed information about living costs, which includes a breakdown of likely living costs in Oxford for items such as food, accommodation and study costs.

Please note that the estimated living costs above are for study in the UK at the University of Oxford. You are advised to contact Scripps Research using the details on their website for information about living costs while studying at the Scripps Research Institute, La Jolla, California, USA.

College preference

Students enrolled on this course will belong to both a department/faculty and a college. Please note that ‘college’ and ‘colleges’ refers to all 43 of the University’s colleges, including those designated as societies and permanent private halls (PPHs). 

If you apply for a place on this course you will have the option to express a preference for one of the colleges listed below, or you can ask us to find a college for you. Before deciding, we suggest that you read our brief introduction to the college system at Oxford and our advice about expressing a college preference

If you are a current Oxford student and you would like to remain at your current Oxford college, you should check whether it is listed below. If it is, you should indicate this preference when you apply. If not, you should contact your college office to ask whether they would be willing to make an exception. Further information about staying at your current college can be found in our Application Guide. 

The following colleges accept students on the DPhil in Biochemistry (Skaggs-Oxford Programme):

Before you apply

Before you begin an application, we recommend that you consult the Medical Sciences Graduate School's website to identify the most suitable course for your intended area of research.

Our guide to getting started provides general advice on how to prepare for and start your application.  You can use our interactive tool to help you evaluate whether your application is likely to be competitive.

Application process

The first stage of admission to the Skaggs-Oxford Programme is administered by Scripps Research.  You should visit the Scripps website for application instructions and deadline information. To apply and for further details about the course you are advised to contact Scripps Research using the details on their website

Your application will be initially assessed by Scripps Research against the 'Admission Guidelines' published on the Scripps Research website. If your application passes this initial assessment, you will be invited to submit an application to the University of Oxford using the standard graduate application procedure.

Application fee - waived for all applications to this course

The application fee of £20, which is usually payable per course application, will be waived for all applications to this course. When you submit your application you will not be shown the screen that collects payment details and you will not need to enter a waiver code.

Do I need to contact anyone before I apply?

We welcome and strongly encourage you to contact potential supervisors that you are interested in working with. The purpose of contacting a supervisor is to learn more about the project and/or lab and determine whether there would be a good fit between what you are looking for and what the lab can offer.

To contact supervisors, begin by looking through the academic profiles and available projects on the department website and identify supervisors you may be interested in working with. Send an email to these potential supervisors indicating that you are interested in applying for a DPhil in their lab. You should explain why you are interested in their project/lab and include any questions you may have about it. 

Further advice on how to contact potential supervisors can be found on the How to find a research supervisor page of the application 'How-to guide'.

If you do not receive a response after two weeks, please send a follow-up email to [email protected]. We encourage you to contact more than one supervisor.

Improving access to graduate study

This course is taking part in initiatives to improve the selection procedure for graduate applications, to ensure that all candidates are evaluated fairly.

Socio-economic data (where it has been provided in the application form) will be used as part of an initiative to contextualise applications at the different stages of the selection process.

Stage 1: Apply to Scripps Research for initial assessment

You must first apply to Scripps Research by the deadline shown in the Scripps application instructions.

How to Apply to Scripps Apply to Scripps

Stage 2: Apply to the University of Oxford

If your application has passed the initial assessment by Scripps Research, you will be invited to complete an application to the University of Oxford. Only candidates who have been invited to proceed should submit an application to the University of Oxford.

You should refer to the information below when completing the application form, paying attention to the specific requirements for the supporting documents.

For this course, the application form will include questions that collect information that would usually be included in a CV/résumé. You should not upload a separate document. If a separate CV/résumé is uploaded, it will be removed from your application.

If any document does not meet the specification, including the stipulated word count, your application may be considered incomplete and not assessed by the academic department. Expand each section to show further details.

Proposed field and title of research project

Under 'Proposed field and title of research project' enter the advertised research project code of your chosen supervisors in order of preference or indicating equal preference. For a list of project codes visit the department's website.

You should not use this field to type out a full research proposal. You will be able to upload your research supporting materials separately if they are required (as described below).

Proposed supervisor

Under 'Proposed supervisor name' enter the names of at least one, and up to three, academics who you would like to supervise your research. You should list them in order of preference or indicate equal preference.

Referees:
Three overall

You do not need to add your referees to your application as the department will receive these from Scripps Research. Please enter Referee1 ([email protected]), Referee2 ([email protected]) and Referee3 ([email protected]) in the referees section and tick the boxes to confirm that you are happy for the referees to be contacted. This should enable you to submit your application.

Whilst you must register three referees, the department may start the assessment of your application if two of the three references are submitted by the course deadline and your application is otherwise complete. Please note that you may still be required to ensure your third referee supplies a reference for consideration.

Official transcript(s)

Your transcripts should give detailed information of the individual grades received in your university-level qualifications to date. You should only upload official documents issued by your institution and any transcript not in English should be accompanied by a certified translation.

More information about the transcript requirement is available in the Application Guide.

Statement of purpose/personal statement:
A maximum of 1,000 words

A personal statement is required and must be in English. You can re-use the statement provided in your Scripps Research application.

If possible, please ensure that the word count is clearly displayed on the document.

Written work

On rare occasions, written work may be requested from some applicants. You will be notified by the department and given more details of the assignment if it is required.

After you've submitted your application

Your application (including the supporting documents outlined above) will be assessed against the entry requirements detailed on this course page. Whether or not you have secured funding will not be taken into consideration when your application is assessed. You can find out more about our shortlisting and selection process in our detailed guide to what happens next.

Find out how to manage your application after submission, using our Applicant Self-Service tool.

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