DPhil in Biochemistry
About the course
This programme aims to train students in cutting-edge laboratory research applying techniques in bionanotechnology, biophysics, computational biology, microscopy, molecular biology, structural biology and systems biology to a broad range of fields including cell biology, chromosome biology, drug discovery, epigenetics, host-pathogen interactions, membrane proteins, ion channels and transporters, and RNA biology.
You will be admitted directly to a particular research area led by departmental members who will be appointed DPhil supervisors. If you are admitted to a particular research supervisor you will not normally do laboratory rotations. You will be based in a research lab and undertake research on a subject agreed with your supervisor.
Examples of research themes can be found on the department's website.
There are no taught courses examined by written papers, however you will have access to a wide range of lecture courses at foundation or preliminary level, as appropriate. If you have changed fields, this will allow you to fill in gaps in your background knowledge. There is also a wide range of courses and workshops which you can attend to acquire skills that will be necessary for the pursuance and presentation of your research, as well as your professional development as a research scientist.
Departmental seminars and colloquia bring students together with academic and other research staff in the department to hear about on-going research, and provide an opportunity for networking and socialising.
The length of the programme ranges from three to four years with the exact duration depending on the following factors as judged by your supervisor(s) and assessors:
- focus and rate of your research development and progress
- achievement of acceptable focus and scope of thesis
- publication quality research
- length of available funding.
A small proportion of DPhil students (about 5%) submit their theses within three years from starting, however on average most students submit within three to four years. By the end of the fourth year, 70-90% of students have submitted their theses.
Research at the Department of Biochemistry is divided into five main themes:
- cell biology, development and genetics
- chromosomal and RNA biology
- infection and disease processes
- microbiology and systems biology
- structural biology and molecular biophysics.
Attendance
The course is full-time and requires attendance in Oxford. Full-time students are subject to the University's Residence requirements.
Provision exists for students on some courses to undertake their research in a ‘well-founded laboratory’ outside of the University. This may require travel to and attendance at a site that is not located in Oxford. Where known, existing collaborations will be outlined on this page. Please read the course information carefully, including the additional information about course fees and costs.
Resources to support your study
As a graduate student, you will have access to the University's wide range of world-class resources including libraries, museums, galleries, digital resources and IT services.
The Bodleian Libraries is the largest library system in the UK. It includes the main Bodleian Library and libraries across Oxford, including major research libraries and faculty, department and institute libraries. Together, the Libraries hold more than 13 million printed items, provide access to e-journals, and contain outstanding special collections including rare books and manuscripts, classical papyri, maps, music, art and printed ephemera.
The University's IT Services is available to all students to support with core university IT systems and tools, as well as many other services and facilities. IT Services also offers a range of IT learning courses for students, to support with learning and research.
You will have access to:
- experimental facilities, as appropriate to your research
- IT support from the Department of Biochemistry
- library services, such as the Radcliffe Science Library and the Cairns Library.
The provision of project-specific resources will be agreed with the relevant supervisor during the planning stages of the research project.
There is the possibility to use facilities in other departments across the division and to access remote facilities at the Rutherford Appleton Laboratory, DIAMOND Light Source and Harwell Science and Innovation Campus.
Supervision
For this course, the allocation of graduate supervision is the responsibility of the Department of Biochemistry and it is not always possible to accommodate the preferences of incoming graduate students to work with a particular member of staff. Under exceptional circumstances a supervisor may be found outside the Department of Biochemistry.
Your supervisor may appoint a senior member of the laboratory as your day-to-day supervisor.
Most students have an opportunity to meet their supervisor on a weekly or fortnightly basis. In addition, Most laboratories also have weekly meetings where members present and discuss their results with other members of the laboratory.
Information about supervisors connected with this course can also be found at the Department of Biochemistry website.
Assessment
You will begin your course as a probationary research student (PRS) and near the end of the first year you will apply to transfer to DPhil (PhD) status. To do this you write a research report and statement of future research plans. This will be assessed by two independent experts, who interview you as part of the process. Continuation in the programme is subject to passing the Transfer of Status exam.
After eight terms of study you will need to apply formally to confirm your DPhil status. This involves writing a short progress report and thesis outline and giving a presentation. The application is assessed by two independent experts. Continuation in the programme is subject to successfully completing the Confirmation of Status.
The final stage of the research programme is submission of your DPhil thesis, which needs to be done within four years. Your thesis is assessed by two independent experts (one of which will be external to the University of Oxford), who conduct a viva examination with you.
Graduate destinations
Approximately 80% of the department’s alumni who completed in the years 2015 to 2019 have pursued a career within academic or industrial research. Other graduates hold positions within a variety of different sectors including Patent Law, Management Consultancy, scientific publishing and teaching.
Changes to this course and your supervision
The University will seek to deliver this course in accordance with the description set out in this course page. However, there may be situations in which it is desirable or necessary for the University to make changes in course provision, either before or after registration. The safety of students, staff and visitors is paramount and major changes to delivery or services may have to be made if a pandemic, epidemic or local health emergency occurs. In addition, in certain circumstances, for example due to visa difficulties or because the health needs of students cannot be met, it may be necessary to make adjustments to course requirements for international study.
Where possible your academic supervisor will not change for the duration of your course. However, it may be necessary to assign a new academic supervisor during the course of study or before registration for reasons which might include illness, sabbatical leave, parental leave or change in employment.
For further information please see our page on changes to courses and the provisions of the student contract regarding changes to courses.
Entry requirements for entry in 2025-26
Proven and potential academic excellence
The requirements described below are specific to this course and apply only in the year of entry that is shown. You can use our interactive tool to help you evaluate whether your application is likely to be competitive.
We know that factors such as socio-economic circumstances and school performance can make it difficult for students to demonstrate their full potential. This course is taking part in an initiative to use contextual data to help us to better understand your achievements in the context of your individual background. For further details, please refer to the information about improving access to graduate study in the How to apply section of this page.
Please be aware that any studentships that are linked to this course may have different or additional requirements and you should read any studentship information carefully before applying. Contextual data may also be used in the assessment of studentships.
Degree-level qualifications
As a minimum, applicants should hold or be predicted to achieve the following UK qualifications or their equivalent:
- a first-class or strong upper second-class undergraduate degree with honours.
The qualification above should be achieved in one of the following subject areas or disciplines:
- biochemistry
- chemistry
- biology
- cell biology
- molecular biology
- biophysics
- physics
- mathematics
- computation.
Please note that entrance is very competitive and most successful applicants have a first-class degree.
A previous master's degree is not required in order to be considered for the programme.
For applicants with a degree from the USA, the minimum overall GPA that is normally required to meet the undergraduate-level requirement is 3.5 out of 4.0. However, most successful applicants have a GPA of 3.7.
If your degree is not from the UK or another country specified above, visit our International Qualifications page for guidance on the qualifications and grades that would usually be considered to meet the University’s minimum entry requirements.
GRE General Test scores
No Graduate Record Examination (GRE) or GMAT scores are sought.
Other qualifications, evidence of excellence and relevant experience
- Applicants are normally expected to have research experience in a biomedical or scientific field. Examples of suitable research experience include, but are not limited to, research projects carried out during previous degree-level study, research internships or work experience as a research assistant.
- A track record demonstrating an interest in research, including the ability to master technical/computational skills, and plan and execute experiments effectively, is likely to advantage your application
- You are expected to have a good understanding of your proposed area of research and be familiar with the recent published work of your proposed supervisor(s)
- Publications are not required but it may strengthen your application if you have already published your work in a scientific journal
English language proficiency
This course requires proficiency in English at the University's standard level. If your first language is not English, you may need to provide evidence that you meet this requirement. The minimum scores required to meet the University's standard level are detailed in the table below.
| Test | Minimum overall score | Minimum score per component |
|---|---|---|
| IELTS Academic (Institution code: 0713) | 7.0 | 6.5 |
TOEFL iBT, including the 'Home Edition' (Institution code: 0490) | 100 | Listening: 22 Reading: 24 Speaking: 25 Writing: 24 |
| C1 Advanced* | 185 | 176 |
| C2 Proficiency† | 185 | 176 |
*Previously known as the Cambridge Certificate of Advanced English or Cambridge English: Advanced (CAE)
†Previously known as the Cambridge Certificate of Proficiency in English or Cambridge English: Proficiency (CPE)
Your test must have been taken no more than two years before the start date of your course. Our Application Guide provides further information about the English language test requirement.
Declaring extenuating circumstances
If your ability to meet the entry requirements has been affected by the COVID-19 pandemic (eg you were awarded an unclassified/ungraded degree) or any other exceptional personal circumstance (eg other illness or bereavement), please refer to the guidance on extenuating circumstances in the Application Guide for information about how to declare this so that your application can be considered appropriately.
References
You will need to register three referees who can give an informed view of your academic ability and suitability for the course. The How to apply section of this page provides details of the types of reference that are required in support of your application for this course and how these will be assessed.
Supporting documents
You will be required to supply supporting documents with your application. The How to apply section of this page provides details of the supporting documents that are required as part of your application for this course and how these will be assessed.
Performance at interview
Interviews are normally held as part of the admissions process.
The main round of interviews is held in January. Additional interviews may be held at later dates subject to the availability of places.
Applications are reviewed by a panel of academics associated with the course. A short-list of applicants is confirmed, based on assessment of achieved or predicted undergraduate degree grade, academic references, personal statement and CV.
Interviews are in person or by video link, take approximately 30 minutes, and are conducted by a panel of at least two interviewers. Applicants are asked to talk about any research project(s) that they may have pursued and questioned on aspects of their research training to date, understanding of the proposed area of study and motivation for undertaking a DPhil.
Offer conditions for successful applications
If you receive an offer of a place at Oxford, your offer will outline any conditions that you need to satisfy and any actions you need to take, together with any associated deadlines. These may include academic conditions, such as achieving a specific final grade in your current degree course. These conditions will usually depend on your individual academic circumstances and may vary between applicants. Our 'After you apply' pages provide more information about offers and conditions.
In addition to any academic conditions which are set, you will also be required to meet the following requirements:
Financial Declaration
If you are offered a place, you will be required to complete a Financial Declaration in order to meet your financial condition of admission.
Disclosure of criminal convictions
In accordance with the University’s obligations towards students and staff, we will ask you to declare any relevant, unspent criminal convictions before you can take up a place at Oxford.
Academic Technology Approval Scheme (ATAS)
Some postgraduate research students in science, engineering and technology subjects will need an Academic Technology Approval Scheme (ATAS) certificate prior to applying for a Student visa (under the Student Route). For some courses, the requirement to apply for an ATAS certificate may depend on your research area.
Other factors governing whether places can be offered
The following factors will also govern whether candidates can be offered places:
- the ability of the University to provide the appropriate supervision for your studies, as outlined under the 'Supervision' heading in the About section of this page;
- the ability of the University to provide appropriate support for your studies (eg through the provision of facilities, resources, teaching and/or research opportunities); and
- minimum and maximum limits to the numbers of students who may be admitted to the University's taught and research programmes.
Biochemistry
The Department of Biochemistry comprises over 45 research groups and around 400 researchers and support staff, including more than 100 graduate students.
The Department of Biochemistry is a vibrant research and teaching department and benefits from state-of-the-art research facilities in its stunning purpose-built building. These include advanced fluorescence microscopy, advanced proteomics, NMR spectroscopy, molecular biophysics, and crystallography.
Research in the department is very broad and encompasses all aspects of modern molecular and cellular biochemistry, from atomic resolution biophysics to cell biology and imaging. The quality of research is outstanding, as demonstrated by an impressive publications output and the international standing of many of the department's researchers.
Funding
For entry in the 2025-26 academic year, the collegiate University expects to offer over 1,000 full or partial graduate scholarships across a wide range of graduate courses.
If you apply by the December deadline shown on this page and receive a course offer, your application will then be considered for Oxford scholarships. For the majority of Oxford scholarships, your application will automatically be assessed against the eligibility criteria, without needing to make a separate application. There are further Oxford scholarships available which have additional eligibility criteria and where you are required to submit a separate application. Most scholarships are awarded on the basis of academic merit and/or potential.
To ensure that you are considered for Oxford scholarships that require a separate application, for which you may be eligible, use our fees, funding and scholarship search tool to identify these opportunities and find out how to apply. Alongside Oxford scholarships, you should also consider other opportunities for which you may be eligible including a range of external funding, loan schemes for postgraduate study and any other scholarships which may also still be available after the December deadline as listed on our fees, funding and scholarship search tool.
Details of college-specific funding opportunities can also be found on individual college websites:
Please refer to the College preference section of this page to identify which of the colleges listed above accept students for this course.
For the majority of college scholarships, it doesn’t matter which college, if any, you state a preference for in your application. If another college is able to offer you a scholarship, your application can be moved to that college if you accept the scholarship. Some college scholarships may require you to state a preference for that college when you apply, so check the eligibility requirements carefully.
Further information about funding opportunities for this course can be found on the department's website.
Costs
Annual fees for entry in 2025-26
Fee status | Annual Course fees |
| Home | £10,070 |
| Overseas | £33,370 |
Information about course fees
Course fees are payable each year, for the duration of your fee liability (your fee liability is the length of time for which you are required to pay course fees). For courses lasting longer than one year, please be aware that fees will usually increase annually. For details, please see our guidance on changes to fees and charges.
Course fees cover your teaching as well as other academic services and facilities provided to support your studies. Unless specified in the additional information section below, course fees do not cover your accommodation, residential costs or other living costs. They also don’t cover any additional costs and charges that are outlined in the additional information below.
Continuation charges
Following the period of fee liability, you may also be required to pay a University continuation charge and a college continuation charge. The University and college continuation charges are shown on the Continuation charges page.
Where can I find further information about fees?
The Fees and Funding section of this website provides further information about course fees, including information about fee status and eligibility and your length of fee liability.
Additional information
There are no compulsory elements of this course that entail additional costs beyond fees (or, after fee liability ends, continuation charges) and living costs. However, please note that, depending on your choice of research topic and the research required to complete it, you may incur additional expenses, such as travel expenses, research expenses, and field trips. You will need to meet these additional costs, although you may be able to apply for small grants from your department and/or college to help you cover some of these expenses.
Living costs
In addition to your course fees and any additional course-specific costs, you will need to ensure that you have adequate funds to support your living costs for the duration of your course.
Living costs for full-time study
For the 2025-26 academic year, the range of likely living costs for a single, full-time student is between £1,425 and £2,035 for each month spent in Oxford. We provide the cost per month so you can multiply up by the number of months you expect to live in Oxford. Depending on your circumstances, you may also need to budget for the costs of a student visa and immigration health surcharge and/or living costs for family members or other dependants that you plan to bring with you to Oxford (assuming that dependant visa eligibility criteria are met).
Further information about living costs
The current economic climate and high national rate of inflation make it very hard to estimate potential changes to the cost of living over the next few years. For study in Oxford beyond the 2025-26 academic year, it is suggested that you budget for potential increases in living expenses of around 4% each year – although this rate may vary depending on the national economic situation. For further information, please consult our more detailed information about living costs, which includes a breakdown of likely living costs in Oxford for items such as food, accommodation and study costs.
College preference
Students enrolled on this course will belong to both a department/faculty and a college. Please note that ‘college’ and ‘colleges’ refers to all 43 of the University’s colleges, including those designated as societies and permanent private halls (PPHs).
If you apply for a place on this course you will have the option to express a preference for one of the colleges listed below, or you can ask us to find a college for you. Before deciding, we suggest that you read our brief introduction to the college system at Oxford and our advice about expressing a college preference.
If you are a current Oxford student and you would like to remain at your current Oxford college, you should check whether it is listed below. If it is, you should indicate this preference when you apply. If not, you should contact your college office to ask whether they would be willing to make an exception. Further information about staying at your current college can be found in our Application Guide.
The following colleges accept students on the DPhil in Biochemistry:
Before you apply
Before you begin an application, we recommend that you consult the Medical Sciences Graduate School's website to identify the most suitable course for your intended area of research.
Our guide to getting started provides general advice on how to prepare for and start your application. You can use our interactive tool to help you evaluate whether your application is likely to be competitive.
If it is important for you to have your application considered under a particular deadline – eg under the December deadline in order to be considered for Oxford scholarships – we recommend that you aim to complete and submit your application at least two weeks in advance. Check the deadlines on this page and the information about deadlines and when to apply in our Application Guide.
Application fee waivers
An application fee of £20 is payable for each application to this course. Application fee waivers are available for the following applicants who meet the eligibility criteria:
- applicants from low-income countries;
- refugees and displaced persons;
- UK applicants from low-income backgrounds; and
- applicants who applied for our Graduate Access Programmes in the past two years and met the eligibility criteria.
You are encouraged to check whether you're eligible for an application fee waiver before you apply.
Readmission for current Oxford graduate taught students
If you're currently studying for an Oxford graduate taught course and apply to this course with no break in your studies, you may be eligible to apply to this course as a readmission applicant. The application fee will be waived for an eligible application of this type. Check whether you're eligible to apply for readmission.
Application fee waivers for eligible associated courses
If you apply to this course and are considering applying (or have already applied) to any of the associated courses listed below, you can request an application fee waiver so that you only need to pay one application fee. We recommend that you use your application fee waiver to apply only for eligible courses that are closely related in research area to this one.
For full details about how to request an application fee waiver, please select the course you are interested in from the list below and refer to the equivalent section of its course page.
The following associated courses are taking part in this application fee waiver scheme:
- Autonomous Intelligent Machines and Systems, EPSRC CDT
- Biomedical and Clinical Sciences (Oxford-GSK), DPhil
- Cancer Science (Biological background), CDT
- Cancer Science (Clinician), DPhil
- Cancer Science (Intercalation), DPhil
- Cancer Science (Maths/Physics background), CDT
- Chemical Synthesis for a Healthy Planet, CDT
- Engineering Biology, BBSRC and EPSRC CDT
- Fundamentals of AI, EIT CDT
- Fusion Power, EPSRC CDT
- Genomic Medicine and Statistics, DPhil
- Healthcare Data Science, EPSRC CDT
- Inflammatory and Musculoskeletal Disease, DPhil
- Inorganic Materials for Advanced Manufacturing, EPSRC CDT
- Intelligent Earth, UKRI CDT in AI for the Environment
- Interdisciplinary Life and Environmental Science, DPhil
- Materials 4.0, EPSRC CDT
- Mathematics of Random Systems: Analysis, Modelling and Algorithms, CDT
- Neuroscience (1+3), DPhil
- Quantum Informatics, EPSRC CDT (expected to open in early-2025)
- Robotics and AI for Net Zero, EPSRC CDT (expected to open in late-2024)
- Statistics and Machine Learning, EPSRC CDT
- Superconductivity: Enabling Transformative Technologies, EPSRC CDT
Do I need to contact anyone before I apply?
We welcome and strongly encourage you to contact potential supervisors that you are interested in working with. The purpose of contacting a supervisor is to learn more about the project and/or lab and determine whether there would be a good fit between what you are looking for and what the lab can offer.
To contact supervisors, begin by looking through the academic profiles and available projects on the department website and identify supervisors you may be interested in working with. Send an email to these potential supervisors indicating that you are interested in applying for a DPhil in their lab. You should explain why you are interested in their project/lab and include any questions you may have about it.
Further advice on how to contact potential supervisors can be found on the How to find a research supervisor page of the application 'How-to guide'.
If you do not receive a response after two weeks, please send a follow-up email to [email protected]. We encourage you to contact more than one supervisor.
Improving access to graduate study
This course is taking part in initiatives to improve the selection procedure for graduate applications, to ensure that all candidates are evaluated fairly. It is taking part in the 'Close the Gap' project which aims to improve access to doctoral study.
Socio-economic data (where it has been provided in the application form) will be used as part of an initiative to contextualise applications at the different stages of the selection process.
Completing your application
You should refer to the information below when completing the application form, paying attention to the specific requirements for the supporting documents.
For this course, the application form will include questions that collect information that would usually be included in a CV/résumé. You should not upload a separate document. If a separate CV/résumé is uploaded, it will be removed from your application.
If any document does not meet the specification, including the stipulated word count, your application may be considered incomplete and not assessed by the academic department. Expand each section to show further details.
Proposed field and title of research project
Under 'Proposed field and title of research project' enter the advertised research project codes of at least one, and up to three chosen supervisors. You should list them in order of preference or indicate equal preference. The project code is shown when you expand the section beneath each supervisor's name on the department's webpage. You should not use this field to provide your own research proposal.
Proposed supervisor
Under 'Proposed supervisor name' enter the names of at least one, and up to three, academics who you would like to supervise your research. You should list them in order of preference or indicate equal preference. The supervisors that you choose should correspond with the projects that you indicated in the previous section.
Referees
Three overall, academic preferred
Whilst you must register three referees, the department may start the assessment of your application if two of the three references are submitted by the course deadline and your application is otherwise complete. Please note that you may still be required to ensure your third referee supplies a reference for consideration.
References should generally be academic though a maximum of one professional reference is acceptable where you have completed an industrial placement or worked in a full-time position. Your references will support intellectual ability, academic achievement, motivation, and your ability to work in a group.
Official transcript(s)
Your transcripts should give detailed information of the individual grades received in your university-level qualifications to date. You should only upload official documents issued by your institution and any transcript not in English should be accompanied by a certified translation.
More information about the transcript requirement is available in the Application Guide.
Statement of purpose/personal statement:
A maximum of 500 words
You should provide a statement of your research interests, in English, describing how your background and research interests relate to the programme. If possible, please ensure that the word count is clearly displayed on the document.
It will be normal for students’ ideas and goals to change in some ways as they undertake their studies, but your personal statement will enable you to demonstrate your current interests and aspirations.
The statement should focus on academic or research-related achievements and interests rather than personal achievements and interests.
This will be assessed for:
- your reasons for applying;
- evidence of motivation for and understanding of the proposed area of study;
- the ability to present a reasoned case in English;
- capacity for sustained and focused work; and
- understanding of problems in the area and ability to construct and defend an argument.
Start or continue your application
You can start or return to an application using the relevant link below. As you complete the form, please refer to the requirements above and consult our Application Guide for advice.
After you've submitted your application
Your application (including the supporting documents outlined above) will be assessed against the entry requirements detailed on this course page. Whether or not you have secured funding will not be taken into consideration when your application is assessed. You can find out more about our shortlisting and selection process in our detailed guide to what happens next.
Find out how to manage your application after submission, using our Applicant Self-Service tool.