Features

Entrance to the COP29 venue, Baku, Azerbaijan

As COP29 gets underway this week (11 - 22 November 2024), we meet the Oxford undergraduate and graduate students who have travelled to Baku to take part in the United Nations Climate Change Conference, and find out what they think should be top of the agenda for decision-makers.

Benjamin Attia is a DPhil researcher in the Smith School of Enterprise and the Environment. His research focuses on improving the description and design of the global climate finance architecture by mapping climate finance flows to the Global South using network science methods.

He said: 'By any definition and under any climate or transition future, there is a massive and growing gap between climate finance flows from the Global North to the Global South and the climate finance needs of the South.

The negotiation of the New Collective Quantified Goal (NCQG) for climate finance tops the agenda for negotiated outcomes of COP29, with key debates around how much the target should be, what kinds of capital should be in scope, who should pay and how that is determined, and what counts towards the target.

Ultimately the setting and implementation of the NCQG is about addressing both climate justice and energy inequality. I hope to see the new target include a number that starts with a 'T' and not a 'B', and for it to account for debt constraints and limited fiscal space of recipients, require more effective crowd-in of private sector investors, and allocate much more concessional capital.'

Ushika Kidd is co-President of Oxford Climate SocietyUshika Kidd is co-President of Oxford Climate Society
Ushika Kidd is a third-year undergraduate Human Scientist focusing on the interface between the climate crisis and health, and co-President of Oxford Climate Society, where she actions her beliefs in interdisciplinary education and grassroots-level collaboration – both of which are powerful enablers to platform local organisations and intersectional perspectives.

She said: 'At COP29 I will be representing student and youth voices, being a key point of contact between researchers in the Oxford delegation and other groups including the Global Alliance of Universities on Climate.

I aim to utilise my experience in environmental journalism to facilitate climate literacy and on-the-ground transparency about key COP29 processes and outcomes through articles and Oxford social media channels so we can push for ambitious global climate finance targets.'

Natasha Lutz is a DPhil student in the Smith School of Enterprise and the Environment and the School of Geography and the Environment at the University of Oxford. Her research uses remote sensing and machine learning to investigate how ecosystem structure and functioning change in response to increased drought and fire occurrence in the temperate and savanna ecosystems of Australia and the Brazilian Cerrado. At COP29 Natasha will be leading an Australian youth delegation to attend and participate in COP29, through Australian Youth for International Climate Engagement (AYFICE). 

She said: 'The first global stocktake at COP28 last year highlighted the gap between current emissions reductions and the levels required, with shortfalls in both policy ambition and implementation.

I'm hoping some agreement can be made to mobilise sufficient funding for affected countries and communities through the New Collective Quantified Goal on climate finance as this is key for creating enabling environments for successful policy implementation. 

Additionally, I am hopeful for progress in the Article 6 negotiations - the use of carbon markets remains a messy space, and clearer guidance under Article 6 is needed.'

Flora Prideaux, a young white lady with long blonde hair standing outside by a brick wallFlora Prideaux is in her third year at Oxford, studying for an undergraduate degree in history
Flora Prideaux is one of the co-presidents of the Oxford Climate Society and a third-year undergraduate history student at Somerville College. 

She said: 'As a 20-year-old undergraduate, I’m excited to help represent Youth voices within our delegation and at COP29 more broadly. I believe that interdisciplinary groups at higher education institutions play a huge role in climate governance processes. I hope to work to facilitate communication between researchers, resources, administration, and undergraduate students at COP through discussions, negotiations, and media resources.

I am also keen to focus on producing accessible information about COP29 itself, particularly for students and young activists, to work to ‘demystify’ COP through videos, social media, and written pieces. I’m excited to work with the other researchers and representatives of Oxford University to help make our goals happen.'

Jodi-Ann Wang, a young Asian lady, speaking at a podium at COP28DPhil candidate Jodi-Ann Wang pictured at COP28. Credit: COP28 UNEP Pavilion
Jodi-Ann Wang is a DPhil candidate in the Oxford Department of International Development. Her research broadly looks at finance and climate justice. This includes investigating the ideologies, political economy, institutions and actors, and power that brought forth the crises of climate change and social inequality.  

She said: 'I will be supporting the Children and Youth Constituency to the UNFCCC, while also presenting some of my latest research around justice and finance in events. With the Constituency, I will be closely tracking the New Collective Quantified Goal (NCQG) on climate finance and the Just Transition Work Programme.

I hope we can reach NCQG outcomes with integrity around who contributes, what amount, as well as transparency and accountability mechanisms that do not compromise the incontrovertible legal obligations of developed countries to contribute. On the Just Transition Work Programme, I hope to see more recognition of historical damages, power imbalance, and how one country's transition can create injustices in other communities.'

Srijani Datta, a young Asian lady with long black hair, standing outside by a hedgeSrijani plans on interviewing young people at COP29
Srijani Datta is a Sociologist interested in urban adaptation and mitigation, specifically with a gender lens. She focuses on public transport, urban commons and nature recovery in cities.  She is also interested in debt reform for achieving climate goals and plans on interviewing young people from the Global South on the topic at COP. 

She said: 'The NCQG is about more than just increasing climate finance - it's much more about the quality of climate finance being mobilised for mitigation and adaptation efforts in Global South countries. I hope at COP29 we are able to focus more on the quality and accountability aspect to be able to create a truly just climate finance regime.'

Sophia Suganuma, a young Asian lady with long black hair.Sophia Suganuma, a Politics, Philosophy, and Economics student.
Sophia Suganuma is a Japanese-Chinese-American social entrepreneur, activist, and Politics, Philosophy, and Economics student at the University of Oxford. She is the Deputy Executive Director of Climate Cardinals, one of the largest youth-led climate advocacy groups, with 16,000 volunteers in 134 nations.  

As the founding Finance Director, Sophia has fundraised nearly half a million USD from groups like Google and L’Oreal, and led partnerships with the World Bank Group Connect4Climate and the World Economic Forum #GenerationRestoration. Her interests include grassroots movements, youth, climate finance, and multilingual climate education. 

Sophia has spoken about her activism at events with the UN Environmental Programme, US NOAA, US FEMA, the US EPA, the Smithsonian, UN Migration, UN Habitat, and UN Food and Agriculture Organization. 

 She said: 'My hope is that the over 1 billion youth around the world are given a platform. We currently receive less than 0.76% of all climate funding. Now, more than ever, corporations, governments, and organizations should fund the future by investing in youth initiatives.'

Pan Ei Ei Phyoe, a young Asian ladyGraduate student Pan Ei Ei Phyoe is a climate and water specialist
Pan Ei Ei Phyoe is a climate and water specialist pursuing her doctorate in Geography and the Environment at Oxford, where her research bridges climate science, policy, and practice to enhance climate resilience in water resource management.

With a focus on the Tana River Basin in Kenya, her work underscores the critical need for tailored climate information to address water challenges in regions prone to climate extremes. Leveraging her background in water resource engineering and social science, she develops an interdisciplinary framework to assess and fulfil water managers’ climate information needs, aiming for sustainable and adaptive water governance.

Previously, she worked as the Climate and Water Specialist at the UNFCCC COP28 Presidency at the UAE. 

She said: 'As COP29 is recognized as the Finance COP this year, I am hopeful that parties will agree on establishing a New Collective Quantified Goal for climate finance, aimed at significantly scaling up funds to support developing nations in their climate adaptation efforts in a measurable and accountable way.'

Emma Somos, a young white lady with light brown hair.Emma Somos, a DPhil student in the Department of Sociology.
Emma Somos is pursuing a DPhil in Sociology at the Department of Sociology. Her research focuses on social stratification, social mobility, economic elites, and the politics of climate change.
She is part of the COP working group at the UK Youth Climate Coalition and works as a Deputy Research Director at Climate Cardinals. She also works as a research assistant at the Blavatnik School of Government, where she also organized the Social Outcomes Conference 2024 working at the Government Outcomes Lab.

She said: 'At COP29, as part of UKYCC’s delegation, I will be campaigning for the negotiation of a comprehensive conflict of interest definition and policy in the UNFCCC to combat the worrying trend of increasing levels of fossil fuel lobbyists entering COP negotiations. New analysis from Kick Big Polluters Out (KBPO) shows that at least 1,773 coal, oil, and gas lobbyists have been granted access to the UN climate negotiations in Baku, outnumbering the delegations of almost every country at the conference. Hopefully for COP30, there will be more transparency required and decreased access for these industries to influence negotiations, which is crucial to achieve fossil fuel phase-out.'

Students in the ROK (South Korea) nation room taking part in remote bilateral negotiations with students assigned to the China nation room

As Oxford’s new academic year gets underway, we take a closer look at an award-winning teaching module that brings students face-to-face with real-world high-stakes decisions. 

What would you do if there was a sudden nuclear threat from North Korea and you were responsible for deciding how your country responded? At Oxford University’s Blavatnik School of Government, Master of Public Policy (MPP) students tackle this challenge head-on in the 'North Korea Crisis Simulation' – an immersive teaching module that represents an innovative approach to teaching public policy.

The one-year postgraduate degree is designed to equip future leaders with practical skills for public policy practice. Its students come from around the world – last year hailing from 58 different countries and diverse backgrounds such as government, NGOs, journalism and academia.

The simulation, which was recognised earlier this year by the Vice-Chancellor’s ‘Innovative Teaching and Assessment’ Award, plunges the MPP students into a complex economic, political, and military crisis on the Korean peninsula; testing their ability to make high-stakes decisions, balance national priorities, manage security concerns, and collaborate with international partners under extreme pressure – all within a world marked by interconnected crises and rising geopolitical competition.

Students assigned to the DPRK (North Korea) room developing strategyStudents assigned to the DPRK (North Korea) room developing strategy

The simulation is the brainchild of Professor Tom Simpson, who has first-hand experience of complex military situations, having served as an officer with the Royal Marine Commandos for five years. It incorporates elements of a ‘war game’, imitating a geopolitical crisis scenario where participants’ actions impact the options available to others.

This simulation challenges students to integrate theoretical knowledge with practical skills, pushing them to perform under high-stakes conditions.

It provides a deeply immersive experience that evolves based on their decisions, enhancing their understanding of national power dynamics. So our students are gaining invaluable insights into real-world policymaking and developing skills directly applicable to their future careers. 


Professor Tom Simpson, Blavatnik School of Government

Split into six teams or countries – USA, China, Japan, Russia, South Korea, and North Korea – the students operate from meticulously designed ‘situation rooms’ complete with national flags, authentic snacks, and tailored props such as national seals on stationery, badges, and door plaques, as well as portraits of national leaders. The rooms are equipped with a bespoke communications suite, giving students the ability to receive recordings and live broadcasts from the dedicated Green Room.

In the weeks leading up to the simulation, MPP students receive detailed background briefings and in-depth reading assignments and research into the history of the crisis, the political, economic, and cultural characteristics of the countries in the region, and the national interests of the six countries involved. But it’s not until 24 hours before the exercise itself begins, when they are presented with confidential instructions, that they learn what their individual roles in the simulation will be. And then, at the start of the simulation, they finally learn about the crisis that is unfolding.

Aoife, a student from Northern Ireland who was assigned the role of the Chief of Staff to the President of the USA said: ‘I got to be a decision-maker at the epicentre of the simulation, which taught me a lot about teamwork, how to handle pressure, and the importance of maintaining focus on your ultimate goal.’

She also reflected on the challenges of working collaboratively in such a pressured environment: ‘It was really eye-opening to be thrown into a scenario where you have only limited information, there’s mistrust across teams, but the stakes are so high that you know you have to find a way of working together.’

Students participating in the breaking news broadcast that concludes the simulationStudents participating in the breaking news broadcast that concludes the simulation
The scenario is managed on the ground by an ‘Exercise Control Team’ comprising Blavatnik teaching staff, comprising a former Assistant Director of the IMF, a professional diplomat and experts on North Korea. They present the participants with team-specific interventions that require real-time reactions, ensuring they consider a wide range of actions – diplomatic, political, economic, military, cyber and intelligence.

While fictional, events in the simulation closely resemble real-world occurrences, such as the abduction of Japanese citizens by North Korea, financial turbulence, and gunfire in the Demilitarised Zone, to emphasise the complexities of real-world decision-making.

Erik, a Ukrainian MPP student, reflected: ‘The most valuable lessons were about teamwork under immense time pressure and responsibility; organising team efforts, balancing each member's involvement with the need to make quick decisions, effectively delegating tasks, and strategic action planning. I learned the importance of being ready to pursue moderate goals, as aiming for maximalist objectives can lead to counterproductive results.’

The award-winning ‘North Korea Crisis Simulation’ is one example of an immersive teaching method that has long been championed by the Blavatnik School’s Case Centre on Public Leadership, which develops teaching materials for public leaders at all career stages, thrusting them into the heart of a range of crises and challenges around the globe. The North Korea Crisis Simulation module has been made freely available for other schools of public policy to download here.

Illustrative concept of a circular battery economy. A hand on the right holds a battery with a charging symbol superimposed. A hand on the left holds three miniature wind turbines and a solar panel. In the centre is a symbol for recycling: three arrows ar

Batteries will play a fundamental role in our journey to Net Zero, but current markets lack the technological and policy infrastructure to ensure batteries are optimally used throughout their full life cycle, including in ‘second life’ applications. The Oxford Martin School Programme on Circular Battery Economies aims to deliver a blueprint for a truly circular battery economy, with a focus on leveraging opportunities in the Global South.

The programme is led by Paul Shearing, Professor of Sustainable Energy Engineering at the Department of Engineering Science and Director of the ZERO Institute. Here, he introduces the programme’s ambitious aims, the opportunities to address multiple challenges across the energy sector, and why Oxford is a natural hub for such crossdisciplinary work.

Professor Paul Shearing, a white man with short brown hair, wearing a black suit and white shirt. He stands in front of a plain grey background.Professor Paul Shearing.
What critical challenge does the programme address, and why is this important now?

Transitioning to electric transport is crucial to achieve global Net Zero goals, and this movement is accelerating rapidly. But what hasn’t happened so quickly is the development of markets and infrastructure to ensure that these batteries are optimally used throughout their lifetime, including at the end of ‘first-life’ service in a vehicle.

Typically, electric vehicle (EV) batteries retain 70-80% of their initial capacity when they reach the end of their useful life in the vehicle. This means they have considerable potential for ‘second life’ purposes, such as for storage for intermittent renewable energy sources including wind and solar. Unfortunately, such ‘second-life’ purposes are currently seldom realised. Because people use their cars in very different ways, there is immense variability in the state of EV batteries once they reach the end of their first life. This leads to uncertainty over the safety and performance of used batteries, limiting their reuse. Since battery recycling remains immature, disposal of EV batteries is fuelling a waste management crisis and loss of critical materials.

Meanwhile, around 760 million people lack access to electricity, mostly living in sub-Saharan Africa and South Asia. Energy storage assets will be crucial to enable these communities to establish zero carbon energy systems. The idea of redeploying used EV batteries as energy storage solutions in emerging economies is highly attractive, since this could deliver three key aims: maximising the economic value of batteries, offsetting the embedded carbon emissions of batteries through maximal use, and supporting the energy transition in developing regions.

Our vision is to support widespread adoption of electrified transportation globally, enable a sustainable circular battery economy, and promote equitable access to clean energy solutions that benefit society.

Professor Paul Shearing

What are the main objectives for the programme?

In summary, our bold vision is to develop a theoretical blueprint for a safe and equitable ‘second-life’ battery industry. Our initial focus will be on India and Africa, where we already have strong established partnerships. We will anchor our work around three integrated multidisciplinary pillars, which will each be developed in deep consultation with stakeholders.

The first focus is to better understand the potential value of a battery circular economy between the Global North and South. This will include mapping global battery flows, quantifying environmental impacts, and evaluating techno-economic cases for battery reuse and repurposing.

Second, we will develop robust tools for battery recertification. Our aim is to establish rapid, cost-effective tests and screening tools to evaluate the state of health and the remaining useful life of EV batteries. Working with stakeholders, we will ensure that these can be easily adopted by end-users. 

Third, we will investigate how policy, institutional, and regulatory landscapes influence the uptake of second-life batteries in emerging economies, and how battery usage relates to wider energy transition goals.

Professor Paul Shearing and Dr Anupama Sen introduce the Oxford Martin Programme on Circular Battery Economies

Developing a circular electric vehicle battery economy mandates a multidisciplinary approach, balancing technical and social sciences, to ensure that proposed interventions are technically viable, sensitive, and people-centric.

Professor Paul Shearing

Who are you collaborating with?

The project has six academic leads. Within the Department of Engineering Science, there is myself, Professor David Howey, Professor Charles Monroe, and Associate Professor Thomas Morstyn. Between us, we have expertise across electrochemical engineering, battery materials development, systems engineering for energy storage systems, battery cell modelling, grid storage modelling, and energy market design.

From the Smith School for Enterprise and Environment, Associate Professor Radhika Khosla and Dr Anupama Sen bring policy expertise (particularly in energy consumption trajectories), urban transitions, and climate change governance in the context of development. Radhika’s position as leader of the Oxford India Centre for Sustainable Development (OICSD) at Somerville College also enables us to leverage a breadth of established contacts throughout India to reach key stakeholders.

Why is Oxford best-placed to lead on this?

We are very proud that Oxford is the birthplace of the lithium-ion battery, thanks to Professor John Goodenough’s work in the 1970s and 80s. Ever since, Oxford has been a global leader in lithium-ion battery research and has developed multidisciplinary strengths in this area.

Additionally, in Oxford- and particularly the Oxford Martin School – there is a real drive to co-develop technological solutions with stakeholders, and road-test these to ensure they are economically viable for communities. This requires integrating many different areas of expertise and Oxford is a wonderful and creative hub for that kind of work. There are not many places where you will find the concentration of expertise to enable such cross-cutting work. This is far more than, say, a chemical engineer working with a mechanical engineer, but a fully interdisciplinary approach across the entire collegiate university. 

There is uncertainty over the safety and performance of used batteries, limiting their reuse. Since battery recycling remains immature, disposal of EV batteries is fuelling a waste management crisis and loss of critical materials.

Professor Paul Shearing

How will the programme help build future capacity, for instance in training new researchers?

The project will recruit several postdoctoral researchers, who will develop a highly transdisciplinary skillset across engineering and physical sciences, economics, modelling, and social sciences. This will equip them to be the future leaders that we need for holistic, just, equitable transitions to Net Zero based on sound technology. It really taps into James Martin’s belief that we need people with wide skillsets and the ability to think in broader contexts to be effective in tackling the big questions confronting us.

More widely, a philosophy of engagement and dissemination is woven throughout the programme. In particular, we aim to disseminate the findings from India and Kenya to empower communities across the Global South to co-create solutions to adopt electric transport and manage critical materials. This will use the extensive contacts we already have built up, particularly through our involvement with the URKI Ayrton Challenge for Energy Storage, where Professor Howey is a member of the strategic leadership group, and the Faraday Institution’s Battery Ambassadors program, which connects us with a network of researchers across 13 countries.

What excites you most about this new work?

As a concept, second life redeployment of EV batteries has been widely discussed for over two decades, but very little practical progress has been made so far. If we can get this right, it can serve as an exemplar for how we can rethink future energy systems to truly embed sustainability and circular economy principles. There will also be much broader lessons for any industry relying on limited critical materials.

When I started my research career, the focus was on developing cheaper batteries with higher energy densities. Now the zeitgeist has moved towards optimising sustainability and circularity. It excites me to be part of a project that will play a major role in setting the discourse of battery research for the next ten years. 

A hand wearing a blue latex glove holds up a petri dish which has colonies of bacteria growing on it. Clear circles can be seen on the plate where an antibiotic has prevented the bacteria from growing. In the background is a stack of petri dishes

Alison Farrar, a DPhil student researching how bacteria respond to antibiotic treatment at the Oxford Martin School, explains how citizen science and artificial intelligence are helping to combat the growing threat of antibiotic resistant bacteria.

Antibiotic resistance poses one of the most urgent challenges to public health worldwide. In this process, bacteria acquire genetic mutations that help them to become resistant to antibiotics. If bacteria become completely resistant to all antibiotics, this treatment will effectively become useless, and simple infections could cause deaths. In fact, this problem is already causing an estimated 1.3 million deaths every year.

One of the biggest challenges is that current testing methods can take up to two days to determine the most effective antibiotic for an infection. The goal of the Oxford Martin Programme on Antimicrobial Resistance Testing was to create a test that detects whether a patient’s bacteria are resistant to antibiotics within an hour. The test works by taking images of a patient’s bacteria under a microscope and using artificial intelligence (AI) to look for any changes that occur when antibiotics are applied to these samples. We recently published results from our citizen science project that investigated what makes some of these bacteria harder for AI to classify.

Alison FarrarAlison Farrar

Image credit: Oxford Martin School

We collected thousands of images of resistant and sensitive bacteria treated with antibiotics. Bacteria that are sensitive to an antibiotic treatment develop changes to their shape, DNA, and cell wall. The AI model learns to detect these changes by studying images of bacteria that have responded to the antibiotic treatment and images of bacteria that don’t.

Sometimes, even though our AI model has seen thousands of images of antibiotic-treated bacteria, it still makes mistakes. In a recent research paper we showed that our current model is about 80% accurate at classifying each Escherichia coli (E. coli) cell. Although this leads to very high confidence when determining whether a whole sample is antibiotic sensitive or resistant, we want our diagnostic test to be as robust as possible.

We noticed that there was some variation in the extent to which E. coli cells changed after the antibiotic treatment, even when they were treated with the same concentration of antibiotic and had the same level of antibiotic resistance. In some cases, cells that looked like a resistant cell were actually sensitive, and vice versa. We started the Infection Inspection project to see which bacterial cells were most likely to be misinterpreted by volunteers, so that we could learn what features might also confuse the AI model. Then, we could focus on understanding those types of cells in our future research. We were also curious whether humans could detect more nuanced features than the AI model.

Volunteers were shown a picture of an E. coli cell that we treated with the antibiotic ciprofloxacin, stained, and imaged with our microscope. Because we grew the E. coli from strains collected at the hospital microbiology laboratory, we knew which strains were sensitive or resistant to ciprofloxacin on standard tests. Equipped with the field guide, volunteers could classify each image as resistant, sensitive, or an image processing error.
We were honoured that more than 5,000 volunteers contributed more than 1 million classifications to our project.

Infection Inspection

How difficult is it to classify a bacterial cell?

To understand which images were most likely to be misclassified as resistant or sensitive, we needed a way to measure whether a volunteer’s classification matched what we expected. We used E. coli cells from 5 clinical strains with different levels of resistance and treated them with different concentrations of ciprofloxacin for 30 minutes. We decided that if a cell was treated with an antibiotic concentration greater than its level of resistance, we expected it to look ‘sensitive’. In contrast, if a cell was treated with an antibiotic concentration less than its level of resistance, we’d expect it to look ‘resistant’. By defining these categories, we could discover when the biology didn’t match these predictions.

As we suspected, there was a lot of variety in how easy a cell was to classify and how well it lined up with our predictions. Some cells were classified correctly every single time, others most of the time, and others almost never. This was true for both ‘resistant’ and ‘sensitive’ cells. We could tell from images of cells that were rarely classified correctly that they had unusual or atypical DNA features.

From our analysis of the volunteer classifications, we couldn’t find any relationship between a volunteer’s accuracy and the number of images they classified or the number of days they were active on the project. It seemed like most of the difficulty of this task comes from the images themselves, rather than a user’s expertise.

AMR Bacteria

What we learned and what comes next

The Infection Inspection project showed us that misclassifications of ciprofloxacin-sensitive and ciprofloxacin-resistant E. coli bacteria are associated with greater diversity in the appearance of the bacterial DNA after antibiotic treatment. It seems like most misclassifications happen when the features don’t line up with what we expect from a ‘sensitive’ or ‘resistant’ cell, rather than our AI misidentifying features.

Even though we expect the bacteria in each of our samples to be genetically identical, there are clearly some cells that respond differently than others. This is an area with lots of open questions that we are designing experiments to answer.

Some volunteers started to notice that in some of our images, it looked like a cell was in the process of cell reproduction. This idea could be related to why some of the bacteria in our samples respond differently than others. It’s possible that the stage of the bacterial life cycle at which the cell is exposed to the antibiotic has an impact on the appearance of the DNA. This is a question we’ll continue to explore in our research.

Thank you

Our group is actively looking into the antibiotic response of many bacterial species to different antibiotics, so that we can develop a rapid test for antibiotic resistance. There is a lot to learn here, and we are extremely grateful to the Zooniverse volunteers who participated. Their enthusiasm and curiosity were extraordinary, so thank you for your dedication and engagement. We’d also like to thank the Zooniverse platform leaders, Helen Spiers, Mary Westwood, and Cliff Johnson, for their expertise and contributions to the development of this project.

IOI DPhil student Shonnette Premchand-Branker preparing plates in the lab at IOI

Antimicrobial resistance (AMR) is one the most pressing challenges facing the world today. Common infections that were once easily treated by antibiotics are becoming life-threatening again. By 2050 it is predicted that over 10 million deaths will be caused by drug-resistant infections every year. 

At the Ineos Oxford Institute for antimicrobial research (IOI), created in 2021 to advance antimicrobial research, Oxford’s graduate students are among those contributing to the search for solutions to tackle this growing threat to global health.

34 DPhil students from around the world are based at the IOI, each part of a focused research project that works to develop new antibiotics or study the spread and impact of AMR around the world.

IOI DPhil student Kate Cook with research assistants Maryam and Firdausi in Kano, NigeriaIOI DPhil student Kate Cook with research assistants Maryam and Firdausi in Kano, Nigeria
Among them is Kate Cook, a DPhil student, who is currently undertaking research in Murtala Muhammad Specialist Hospital in Kano, Nigeria to investigate the causes of wound infections in surgical and orthopedic wards. Through her work, she aims to understand the role of insects like flies, cockroaches and ants in spreading bacteria in tropical climates.

Working closely with two research assistants in the hospital – Maryam and Firdausi – Kate acts as a microbiological detective, identifying which kinds of bacteria are causing infections in patients, then investigating whether these bacteria are also present on hospital surfaces, and in insects caught on the wards.

“Designing creative experiments is the best part of my work. It can be challenging when there are huge numbers of samples to analyse, and trying to figure out how the bacterial transmission networks fit together, but the project is very rewarding. The opportunity to work with the team in Kano, who are equally as passionate about the project has been amazing.”

IOI DPhil student Shonnette Premchand-Branker preparing plates in the lab at IOIIOI DPhil student Shonnette Premchand-Branker preparing plates in the lab
Insects – specifically flies – are also of interest to PhD student Shonnette Premchand-Branker. She is part of an IOI study investigating the role of flies in spreading antibiotic resistance in hospitals, where the use of antibiotics is high, as is the number of diagnosed multidrug-resistant infections in patients. 

A microbiologist by training, Shonnette analyses fly samples which will be collected from countries across the globe.

“The flies are sent to our lab in Oxford after they have been collected and labelled in hospitals. They arrive whole, so our first step is to homogenise them, which basically means we make fly juice. The next step is to prepare bacterial cultures, and then extract and sequence their DNA. We’re looking for antimicrobial resistance genes that we know are related to multidrug-resistant infections.”

IOI DPhil student Chy Akpulu preparing samples for analysis in the lab at IOIIOI DPhil student Chy Akpulu preparing samples for analysis in the lab at IOI
Nigerian-born DPhil student, Chinenye ‘Chy’ Akpulu, works as part of the IOI study Burden of Antibiotic Resistance in Neonates from Developing Societies (BARNARDS). The study aims to reduce the prevalence of neonatal sepsis, and Chy is studying if the presence of antibiotic-resistant bacteria in babies could be linked to their gut microbiome, the community of bacteria that live in their stomachs.

The work is potentially life-saving – antibiotic resistance to sepsis is a leading cause of deaths in newborns, with 99% of global newborn mortality occurring in low-and-middle income countries.

“I am drawn to research that directly benefits people, and the work that the BARNARDS team were doing really resonated with me - not just scientific enquiry but helping the community itself by translating research into better clinical outcomes.”

Wojtek Treyde, a PhD student who has previously studied at the University of Heidelberg in Germany is part of the INEOS Oxbridge Doctoral Initiative on Antimicrobial Resistance – a fully funded DPhil programme that enables up to seven candidates to study at both the universities of Oxford and Cambridge.

Wojtek is a computational chemist working on drug development. His PhD project combines his research experience so far – an undergraduate degree in chemistry and master’s degree with a focus in Machine Learning.

A branch of chemistry, computational chemistry uses computer simulations to solve complex chemical challenges, such as the discovery of new antibiotics to tackle rising rates of AMR. Wojtek works closely with lab-based researchers at the IOI to use machine learning to inform research.

“I wanted to use my training in an area where I could make a difference. Alongside climate change, AMR is the biggest threat facing humanity and I want to contribute to finding new solutions.”

Find out more about the work of IOI here.