A student in a lab coat cutting DNA
Cutting DNA bands from an agarose gel in the laboratory
(Image Credit: Laurynas Pliuskys / Graduate Photography Competition)

DPhil in Molecular Cell Biology in Health and Disease

About the course

You will spend up to four years in one of the department's many research groups, working on a project supervised by the group's principal investigator. During this period you will have the opportunity to take part in the comprehensive training programme organised for graduate students.

After a very short induction period of one or two weeks, during which some basic training is provided, you will start a research project in your supervisor’s laboratory.

There are a number of key stages in the research programme.

  1. Within a month of starting, you will meet with your supervisor and graduate advisor to finalise your project and agree on an initial programme of research.
  2. Within the first three months, you will complete an analysis of your training needs with your supervisor.
  3. Within the first six months you are expected to complete a literature review on a topic relating to your area of research. 
  4.  After one year you will apply to transfer to DPhil status. (See Assessment)
  5. You will apply to confirm your DPhil status by the end of your third year. (See Assessment)
  6. The final stage is submission of your DPhil thesis, which needs to be done within four years.

Most laboratories have weekly meetings where members present and discuss their research results with other members of the laboratory. You will also present your work in progress seminars, which are attended by other research groups working in related areas. 

Whilst working on your research project you will participate in a comprehensive, flexible skills training programme which includes a range of workshops and seminars in transferable skills, generic research skills and specific research techniques. 

There are a wide range of events organised for DPhil students. All students participate in an annual graduate students' symposium, which is attended by the entire department. Student contributions are carefully evaluated and prizes are awarded to the best posters or presentations in each year.

You will also have access to the extensive range of seminars and symposia in this and other departments at the University. During term-time there are departmental seminars which all graduate students are expected to attend. Your research group will be able to advise you as to which seminar series you should attend. All seminars are advertised on the web portal Oxford Talks. There are multiple opportunities for students to present their work, including the annual Departmental Graduate Student Symposium, and other Student Symposia within the University. All students have opportunities to present their work at national and international conferences.

Attendance

The course is full-time and requires attendance in Oxford. Full-time students are subject to the University's Residence requirements.

Provision exists for students on some courses to undertake their research in a ‘well-founded laboratory’ outside of the University. This may require travel to and attendance at a site that is not located in Oxford. Where known, existing collaborations will be outlined on this page. Please read the course information carefully, including the additional information about course fees and costs.

Resources to support your study

As a graduate student, you will have access to the University's wide range of world-class resources including libraries, museums, galleries, digital resources and IT services.

The Bodleian Libraries is the largest library system in the UK. It includes the main Bodleian Library and libraries across Oxford, including major research libraries and faculty, department and institute libraries. Together, the Libraries hold more than 13 million printed items, provide access to e-journals, and contain outstanding special collections including rare books and manuscripts, classical papyri, maps, music, art and printed ephemera.

The University's IT Services is available to all students to support with core university IT systems and tools, as well as many other services and facilities. IT Services also offers a range of IT learning courses for students, to support with learning and research.

You will be provided with plenty of bench space in your supervisor's laboratory and a suitable desk. The laboratories are all newly-refurbished, spacious and well equipped. There are central facilities for flow cytometry, microscopy, surface plasmon resonance, and genome engineering. Members of the department also have access to a wide range of shared facilities in the science area, including proteomics, imaging, structural biology, genomics, and drug-discovery. Training and support is available for use of all these resources. You will have your own computer and have access to the department’s IT infrastructure and servers. You will also have use of University Libraries such as the Radcliffe Science Library and the Cairns Library. Library access includes full online access to all relevant scientific journals.

Supervision

The allocation of graduate supervision for this course is the responsibility of the Sir William Dunn School of Pathology and it is not always possible to accommodate the preferences of incoming graduate students to work with a particular member of staff. Under exceptional circumstances a supervisor may be found outside the Sir William Dunn School of Pathology. 

You will be supervised by a team that includes your main supervisor, other supervisors, such as your graduate advisor, and the Director of Graduate Studies. Your graduate adviser will usually be another experienced principal investigator in the department. Your supervisor may appoint a senior member of the laboratory as your day-to-day supervisor. Further support is available from your college advisor.

Assessment

There are two formal assessments that need to be passed before you are able to submit your DPhil Thesis. 

In Oxford all research students start out holding probationary research student (PRS) status.

You need to transfer to DPhil status within four terms (about 15 months). To do this you write a report describing your research to date and plans for the future. This will be assessed by two independent experts, who interview you as part of the process.

You need to confirm your DPhil status within three years. This involves writing a short progress report and thesis outline and giving a presentation. The application is assessed by two experts.

The final stage is submission of your DPhil thesis, which needs to be done within four years. This is assessed by two experts in the field, one of whom is external to Oxford. The assessment includes an interview or viva.

Graduate destinations

The majority of graduates from the DPhil in Molecular Cell Biology in Health and Disease (previously the DPhil in Pathology) pursue research careers in academic institutions or industry. Graduates also pursue careers in management (in pharmaceutical or biotechnology companies), consulting, law, teaching, scientific publishing, medical writing, and with science funding organisations and, charities.

Changes to this course and your supervision

The University will seek to deliver this course in accordance with the description set out in this course page. However, there may be situations in which it is desirable or necessary for the University to make changes in course provision, either before or after registration. The safety of students, staff and visitors is paramount and major changes to delivery or services may have to be made if a pandemic, epidemic or local health emergency occurs. In addition, in certain circumstances, for example due to visa difficulties or because the health needs of students cannot be met, it may be necessary to make adjustments to course requirements for international study.

Where possible your academic supervisor will not change for the duration of your course. However, it may be necessary to assign a new academic supervisor during the course of study or before registration for reasons which might include illness, sabbatical leave, parental leave or change in employment.

For further information please see our page on changes to courses and the provisions of the student contract regarding changes to courses.

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